This is a fascinating story that will keep you enthralled long after you've turned the last page. Anna is 13. She was conceived in vitro, specifically to be a donor for her older sister, who has a rare form of leukemia. At first, it's only intended that she will donate cord blood, but then Kate needs blood, and platelets, and bone marrow, and each time, Anna finds herself in the hospital, sharing her healthy cells with her sister, though no one ever asks if she wants to. When it's assumed she'll donate a kidney, she hires an attorney and sues for the right to control her own body, sending this dysfunctional family further askew. Every member of the family is a point-of-view character (including an older brother who works out his anxiety by committing arson, and his firefighter father). I tell beginning writers that an author can rarely pull off more than three POV characters, but Picoult is proof that all rules can be broken successfully. Each character is real and fully drawn (except Mom; she felt a little flat to me). You will empathize with all of them. For the time you are in a specific character's head, you will believe their POV is clearly, obviously the only right one. When Anna speaks, you won't understand why her parents are treating her so horribly. When Kate speaks, you won't understand why Anna doesn't joyfully give up the kidney, both kidneys if necessary! When the brother speaks, your heart will ache for this forgotten child who feels the need to destroy. When his father speaks, you will yearn for Anna to drop the legal battle, to understand how you love all your children and cannot lose any of them. Hence the tensions that tear this family apart will play out in your heart as you read. One warning though: the end of the book is a body blow. Be alone when you read the last few chapters (or at least somewhere private).